Director of Bioconjugation

The Director of Bioconjugation will assume responsibility for the following activities:

1. Daily management of the department and coordination with other groups.
2. Definition and execution of work plans for each project.
3. Training and assessment of staff, improvement and retention of technical expertise.
4. Process development of antibody drug conjugates (ADCs).
5. Developing novel conjugation platforms, keeping pace with novel technologies.
6. Execution of manufacturability assessments supporting Client’s early needs.
7. Supporting business development; serving as a subject matter expert (SME).
8. Troubleshooting conjugation processes that fall outside of platform-able design spaces.
9. Drafting technology transfers, development reports, and CMC sections.
10. Assisting other groups (AD, QC, QA, MFG) with method development and confirmation.

The desired requirements for this position are as follows:

1. PhD in Organic Chemistry, Pharmaceutical Synthesis, Biology, or related field.
2. At least 5 years of direct experience in downstream process development, including antibody purification and conjugation.
3. At least 5 years of experience directly managing reports.
4. Experience with regulatory filings is desirable.
5. Experience with commonly used toxins and antibody-drug conjugates.
6. Working knowledge of small molecule registration, shipment, and declaration.